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Christina Applegate's Multiple Sclerosis Battle: Everything She's Said About Fighting the Disease

Of the disease, Christina Applegate candidly said, "I'm never gonna wake up and go, 'This is awesome.'"

In August 2021 at the age of 49, Applegate announced she had been diagnosed with multiple sclerosis -- commonly referred to as MS-- a "potentially disabling disease of the brain and spinal cord (central nervous system)," according to the Mayo Clinic. Following the postponement of the 2023 Emmys to January 2024, Applegate received the warmest of welcomes when she stepped out onto the stage as the first presenter that night, accompanied by host Anthony Anderson, to a standing ovation. Getty ImagesDespite offering up punchlines, Applegate has not minced words about her experience with MS. During her interview with Roberts, she said quite plainly,"I live kind of in hell."

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