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Christina Applegate Says She Hasn't Showered in Three Weeks and Her 'Legs Are Done' Amid Painful MS Relapse

In August 2021, Applegate announced she had been diagnosed with multiple sclerosis.

In response to Sigler's inquiry about the nature of her relapse, Applegate described intense pain in her legs, making simple tasks like walking to the bathroom feel perilous. Getty ImagesThe actress disclosed the toll the relapse has taken on her mental health, revealing that she recently experienced a deep depression upon returning from what she described as a "win vacation." Applegate's emotional struggles were further compounded by her admission that she hadn't showered in three weeks due to her debilitating condition, relying instead on alternative hygiene methods such as using Cottonelle.

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