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Christina Applegate Says Her Heart Breaks Thinking It Would Be Easier If She Was 'Not Here' Amid MS Battle

Applegate and her 'MeSsy' podcast co-host, Jamie-Lynn Sigler, detail how their MS diagnoses affect their bodies.

Applegate, who recalled how a "strange superpower" motivated her to walk without her cane during the family trip, lamented how her burst of energy resulted in a severe lack of strength afterward, which her daughter noticed. Applegate first went public with her multiple sclerosis diagnosis in August 2021 -- a "potentially disabling disease of the brain and spinal cord (central nervous system)," according to the Mayo Clinic. "For so long, I have been celebrated for being the strong one and the positive one that it felt like I was not that if I would admit that some days were hard," Sigler told Good Morning America's Robin Roberts in an intimate sit-down interview last month.

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