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Christina Applegate admits she is grappling with 'real, f**k it all' depression as she copes with multiple sclerosis battle


On the podcast she shares with friend Jamie Lynn-Sigler, Messy, Christina admitted she has been in a 'real, f**k it all' depression that has begun to scare her.

Christina Applegate candidly described the mental anguish she had been feeling amid her battle with multiple sclerosis, admitting she had been in a 'real' depression as she copes with her chronic condition Jamie, 43, who also suffers from multiple sclerosis, advised her friend to avoid comparing her current state to her past: 'It's so hard to live in a disabled body. The episode - which was recorded in early 2024 - also saw Christina, 52, reflect on her appearance at the Emmys , which she described as the most challenging day of her life; pictured

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