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Lady Gaga and fiancé Michael Polansky announce a new AI-powered biotech venture that uses living human skin tissue to help discover better skincare ingredients

Outer Bio is a skin bioactives discovery platform advancing the future of skincare ingredients. We combine machine learning, human skin models, and full-thickness living human tissue to discover and validate next-generation skincare actives. Our platform enables cosmetic R&D teams to test compounds in real human skin biology that remains viable for weeks, far beyond traditional in vitro models. By moving beyond outdated testing systems, Outer Bio accelerates the discovery of novel bioactive compounds, active skincare ingredients, and clinically relevant skin actives. The skincare industry has long relied on legacy ingredients with limited innovation. Outer Bio introduces a new discovery engine for cosmetic science, identifying high-performance bioactives with proven efficacy in living skin. Built for modern skincare R&D, powered by real human biology.

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